Biomarker Significance of Interleukin-18 in Juvenile Idiopathic Arthritis

Multicentric Carpotarsal Osteolysis Mimicking Juvenile Idiopathic Arthritis

Background Multicentric carpotarsal osteolysis (MCTO), a skeletal dysplasia presents in early childhood mimicking juvenile idiopathic arthritis (JIA). Recognition of this syndrome is essential to avoid unnecessary treatment with immunosuppressive agents because of different course and treatment. Case Report A 3-year-old boy presented with swelling and restriction of right wrist joint and left ...

Clinical significance of anticardiolipin antibodies in juvenile idiopathic arthritis.

OBJECTIVE Anticardiolipin antibodies (aCL) have been demonstrated in a large spectrum of autoimmune diseases. However, its occurrence in childhood, in particular in juvenile idiopathic arthritis (JIA), is not well established. The present study addressed the frequency and clinical significance of aCL in a group of JIA patients. METHODS aCL (IgG and IgM isotypes), antinuclear antibodies (ANA),...

Polymorphisms within interleukin 15 are associated with juvenile idiopathic arthritis.

Juvenile idiopathic arthritis.

Juvenile idiopathic arthritis (JIA), a term referring to a group of disorders characterized by chronic arthritis, is the most common chronic rheumatic illness in children and is a significant cause of short- and long-term disability. This article discusses the classification, differential diagnosis, and treatment of JIA.

Juvenile Idiopathic Arthritis